一、中心簡(jiǎn)介
首都醫(yī)學(xué)科學(xué)創(chuàng)新中心（簡(jiǎn)稱創(chuàng)新中心）是北京市新成立的具有獨(dú)立法人資格的新型研發(fā)機(jī)構(gòu)。創(chuàng)新中心以推動(dòng)醫(yī)學(xué)科學(xué)發(fā)展、改善人類健康為目標(biāo)，開展生物醫(yī)學(xué)研究，致力于提升醫(yī)學(xué)科學(xué)創(chuàng)新與成果轉(zhuǎn)化能力，提高疾病診斷和治療水平。我們將匯聚世界高水平科學(xué)家，與首都醫(yī)學(xué)教育和科學(xué)研究?jī)?yōu)質(zhì)資源緊密合作，打造多學(xué)科交叉融合的科研平臺(tái)，綜合自由探索、醫(yī)學(xué)目標(biāo)導(dǎo)向、有組織科研等途徑，實(shí)踐新型科研模式和體制機(jī)制，逐步推進(jìn)醫(yī)教研產(chǎn)的深度融合，培養(yǎng)適應(yīng)醫(yī)學(xué)科學(xué)創(chuàng)新發(fā)展的優(yōu)秀人才。
二、實(shí)驗(yàn)室介紹
首都醫(yī)學(xué)科學(xué)創(chuàng)新中心免疫研究所孫少聰實(shí)驗(yàn)室招聘博士后或副研究員以開展癌癥免疫和自身免疫的基礎(chǔ)和轉(zhuǎn)化研究。本實(shí)驗(yàn)室長(zhǎng)期致力于T細(xì)胞的功能和機(jī)制研究。使用信號(hào)轉(zhuǎn)導(dǎo)，CRISPR基因篩選，單細(xì)胞RNA測(cè)序，和基因敲除小鼠等多種方法研究T細(xì)胞激活，分化，效應(yīng)功能和耗竭的分子機(jī)理，從而鑒定關(guān)鍵性T細(xì)胞調(diào)節(jié)因子。近期工作還包括運(yùn)用生物信息學(xué)手段分析癌癥患者腫瘤測(cè)序數(shù)據(jù)庫(kù)，鑒定癌癥免疫調(diào)節(jié)因子，然后用小鼠模型進(jìn)行機(jī)理研究。自身免疫研究包括多發(fā)行硬化癥，SLE，和腸炎的小鼠模型。
三、代表性論文
Nature Cell Biology 24: 1165-1176, 2022, PMID: 35773432
Nature Immunology 22: 193-204, 2021, PMID: 33398181
Nature Cell Biology 21: 1604-1614, 2019, PMID: 31792381
Nature Immunology 20: 879-889, 2019, PMID: 31182807
Nature Immunology 19: 1224-1235, 2018, PMID: 30250187
Nature 545: 365-369, 2017, PMID: 28489822
Nature Immunology 17: 259-268, 2016, PMID: 26808229
Nature Immunology 15: 562-570, 2014, PMID: 24777531
Immunity 40: 692-705, 2014, PMID: 24792914
Nature Medicine 19: 595-602, 2013, PMID: 23603814
Nature 494: 371-374, 2013, PMID: 23334419
四、博士后/副研究員
01、崗位職責(zé)
1.獨(dú)立開展和參與實(shí)驗(yàn)室課題研究工作；
2.協(xié)助PI指導(dǎo)研究生工作。
02、任職要求
1.具有免疫學(xué)相關(guān)領(lǐng)域研究背景，即將或已經(jīng)獲得博士學(xué)位；副研究員需要有博士后研究經(jīng)歷；
2.具備獨(dú)立開展科研工作和指導(dǎo)研究生能力，具有科研熱情和嚴(yán)謹(jǐn)?shù)目蒲袘B(tài)度；
3.具備熟練的英文交流和讀寫能力，可以獨(dú)立撰寫英文論文；
4.有扎實(shí)的免疫學(xué)、信息生物學(xué)、小鼠腫瘤免疫或自身免疫模型試驗(yàn)背景者優(yōu)先考慮。
五、福利待遇
1.根據(jù)應(yīng)聘者的工作經(jīng)驗(yàn)和能力，提供具有市場(chǎng)競(jìng)爭(zhēng)力的薪酬（詳情面談）；
2.享受五險(xiǎn)一金、帶薪年假、體檢和補(bǔ)充醫(yī)療保險(xiǎn)等；
3.支持個(gè)人職業(yè)發(fā)展，提供必要的工作相關(guān)專業(yè)培訓(xùn)。
六、申請(qǐng)方法
應(yīng)聘者請(qǐng)將個(gè)人簡(jiǎn)歷、研究興趣或計(jì)劃，以及2-3名推薦人的姓名及聯(lián)系方式，以及其他能證明科研能力的相關(guān)電子文件發(fā)送到郵箱 ssun@cimrbj.ac.cn，請(qǐng)【點(diǎn)擊下方“立即投遞/投遞簡(jiǎn)歷”，即刻進(jìn)行職位報(bào)名】，郵件主題請(qǐng)注明“應(yīng)聘者名字+具體應(yīng)聘職位”。
聯(lián)系人：
聯(lián)系地址：北京市豐臺(tái)區(qū)右安門外西頭條10號(hào)-首都醫(yī)學(xué)科學(xué)創(chuàng)新中心
本招聘長(zhǎng)期有效，至招聘到合適人選為止。
ABOUT CIMR
Chinese Institutes for
Medical Research (CIMR) is a newly founded institution dedicated to fundamental
and translational medical research.The CIMR is located at the main campus of
the
Laboratory Introduction
The laboratory of Shao-Cong Sun at the Chinese Institutes for Medical Research (CIMR) is recruiting motivated Postdoctoral Fellows and Research Associate Investigators to conduct basic and translational research in Cancer Immunology and Autoimmunity.A major focus of the lab is to study the molecular mechanisms that regulate T cell activation, differentiation, effector function, and exhaustion using a variety of cutting-edge techniques, such as signal transduction, CRISPR library screening, single-cell RNA sequencing, and knockout mouse models.Our recent work also includes the use of bioinformatics to analyze tumor sequencing databases of cancer patients, identify cancer immunomodulators, and then conduct mechanistic studies using mouse models.Autoimmune studies include mouse models of multiple sclerosis, SLE, and colitis.Professor Sun's team has made many significant contributions in this field, including the discovery of key factors regulating T cell functions in autoimmunity and cancer immunity.Our work also has strong translational potential and plays an important guiding role in drug development and disease treatment.The laboratory also uses mouse models of cancer immunotherapy to conduct translational studies and explore improved methods of immunotherapy.
Representative Publications
Nature Cell Biology 24: 1165-1176, 2022, PMID: 35773432
Nature Immunology 22: 193-204, 2021, PMID: 33398181
Nature Cell Biology 21: 1604-1614, 2019, PMID: 31792381
Nature Immunology 20: 879-889, 2019, PMID: 31182807
Nature Immunology 19: 1224-1235, 2018, PMID: 30250187
Nature 545: 365-369, 2017, PMID: 28489822
Nature Immunology 17: 259-268, 2016, PMID: 26808229
Nature Immunology 15: 562-570, 2014, PMID: 24777531
Immunity 40: 692-705, 2014, PMID: 24792914
Nature Medicine 19: 595-602, 2013, PMID: 23603814
Nature 494: 371-374, 2013, PMID: 23334419
Open Positions
Postdoctoral Fellows /
Research Associate Investigators
Main Responsibilities
a.Carrying out research projects independently.
b.Assisting PI to mentor graduate student.
Qualifications
a.With research background in immunology related biomedical fields, either about to obtain or having already obtained a doctoral degree; postdoctoral experience is required for research associate investigator position.
b.With motivation and ability to independently carry out research projects and supervise graduate students, and have strong motivation in scientific research.
c.Proficient in English reading, writing, and daily communication; capable of writing papers in English.
d.Those with solid background in immunology, bioinformatics, mouse models of cancer immunity or autoimmunity, or CRISPR screen will be given priority.
Welfare Treatment
a.Provide competitive salary based on the applicant’s work experience and ability (salary negotiable).
b.Provide social insurance and housing fund, supplementary medical insurance, physical examination and paid annual leave.
c.Support career development, provide relevant professional guidance.
How to apply
To apply, please send personal resume, research interest or plan, the names and contacts of 2-3 referees and other materials demonstrating research capabilities to ssun@cimrbj.ac.cn, and indicate the applicant's name and specific job position in the email subject.
Contact person: Dr.Sun
This recruitment is valid for the long term until a suitable candidate is recruited.
信息來(lái)源于網(wǎng)絡(luò)，如有變更請(qǐng)以原發(fā)布者為準(zhǔn)。
來(lái)源鏈接：
https://mp.weixin.qq.com/s/826vE_T8fw2KtdqX0VhpQQ
更多最新博士后招收資訊請(qǐng)關(guān)注：
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